Detalhe da pesquisa
1.
sc2MeNetDrug: A computational tool to uncover inter-cell signaling targets and identify relevant drugs based on single cell RNA-seq data.
PLoS Comput Biol
; 20(1): e1011785, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38181047
2.
Proteins in Tumor-Derived Plasma Extracellular Vesicles Indicate Tumor Origin.
Mol Cell Proteomics
; 22(1): 100476, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36470535
3.
Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology.
Cancer Immunol Immunother
; 72(8): 2813-2827, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37179276
4.
T Cell- and Monocyte-Specific RNA-Sequencing Analysis in Septic and Nonseptic Critically Ill Patients and in Patients with Cancer.
J Immunol
; 203(7): 1897-1908, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31484735
5.
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial.
Lancet Oncol
; 17(5): 651-62, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27055731
6.
Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer.
Cancer Immunol Immunother
; 63(5): 513-28, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24652403
7.
The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer.
Sci Rep
; 14(1): 6373, 2024 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493257
8.
Single-cell transcriptomics reveals long noncoding RNAs associated with tumor biology and the microenvironment in pancreatic cancer.
NAR Cancer
; 5(4): zcad055, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38023733
9.
Engineering a Novel Modular Adenoviral mRNA Delivery Platform Based on Tag/Catcher Bioconjugation.
Viruses
; 15(11)2023 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38005953
10.
Computational prediction of MHC anchor locations guides neoantigen identification and prioritization.
Sci Immunol
; 8(82): eabg2200, 2023 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37027480
11.
High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival.
NPJ Precis Oncol
; 7(1): 105, 2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37857854
12.
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment.
J Immunother Cancer
; 11(7)2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37487666
13.
Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer.
Front Immunol
; 13: 1039226, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36569934
14.
Challenges targeting cancer neoantigens in 2021: a systematic literature review.
Expert Rev Vaccines
; 20(7): 827-837, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34047245
15.
Neoantigen vaccine platforms in clinical development: understanding the future of personalized immunotherapy.
Expert Opin Investig Drugs
; 30(5): 529-541, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33641576
16.
Tumor-on-chip modeling of organ-specific cancer and metastasis.
Adv Drug Deliv Rev
; 175: 113798, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34015419
17.
In silico epitope prediction analyses highlight the potential for distracting antigen immunodominance with allogeneic cancer vaccines.
Cancer Res Commun
; 1(2): 115-126, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35611186
18.
Neoadjuvant FOLFIRINOX Therapy Is Associated with Increased Effector T Cells and Reduced Suppressor Cells in Patients with Pancreatic Cancer.
Clin Cancer Res
; 27(24): 6761-6771, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34593529
19.
Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation.
Genome Med
; 13(1): 56, 2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33879241
20.
Tumor-on-a-chip platform to interrogate the role of macrophages in tumor progression.
Integr Biol (Camb)
; 12(9): 221-232, 2020 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32930334